%0 Journal Article
%A Ito, Shotaro
%A Goseki, Raita
%A Ishizone, Takashi
%A Senda, Saeko
%A Hirao, Akira
%D 2013
%T Successive Synthesis of
Miktoarm Star Polymers Having up to Seven Arms by a New Iterative
Methodology Based on Living Anionic Polymerization Using a Trifunctional
Lithium Reagent
%U https://acs.figshare.com/articles/journal_contribution/Successive_Synthesis_of_Miktoarm_Star_Polymers_Having_up_to_Seven_Arms_by_a_New_Iterative_Methodology_Based_on_Living_Anionic_Polymerization_Using_a_Trifunctional_Lithium_Reagent/2445271
%R 10.1021/ma3024975.s001
%2 https://acs.figshare.com/ndownloader/files/4087942
%K reaction sequence
%K TBDMS
%K ABCDE
%K THP
%K Living Anionic Polymerization
%K 2B
%K Trifunctional Lithium ReagentA
%K methacrylate
%K core agent access
%K PA
%K Miktoarm Star Polymers
%K TMS
%K reaction sites step
%K poly
%K ABCDEFG
%K New Iterative Methodology
%K ABCDEF
%K ABC
%K ABCD
%K trifunctional lithium reagent
%X A new stepwise iterative methodology based on living
anionic polymerization using a trifunctional lithium reagent substituted
with trimethylsilyl (TMS), tert-butyldimethylsilyl
(TBDMS), and tetrahydropyranyl (THP) ethers of protected hydroxyl
functionalities has been developed in order to obtain synthetically
challenging many-armed μ-star polymers. In each reaction sequence
of the new methodology, these three ether functions were selectively
deprotected in turn under carefully selected conditions as designed,
followed by conversion to three α-phenyl acrylate (PA) reaction
sites step by step at different reaction stages. They were used for
the introduction of two different arm segments and the reintroduction
of the above same three ethers. This reaction sequence was repeated
three times to successively synthesize 3-arm ABC, 4-arm ABCD, 5-arm
ABCDE, 6-arm ABCDEF, and 7-arm ABCDEFG μ-star polymers with
well-defined structures. Herein, the A, B, C, D, E, F, and G arms
were poly(cyclohexyl methacrylate), polystyrene, poly(4-methoxystyrene),
poly(4-methylstyrene), poly(methyl methacrylate), poly(ethyl methacrylate),
and poly(2-methoxyethyl methacrylate) segments, respectively. The
trifunctional lithium reagent was also demonstrated to satisfactorily
function as a convenient and useful core agent access to the general
synthesis of 4-arm ABCD and 6-arm A2B2C2 μ-star polymers.
%I ACS Publications