%0 Journal Article
%A Zhang, Yongda
%A Li, Ning
%A Qu, Bo
%A Ma, Shengli
%A Lee, Heewon
%A Gonnella, Nina C.
%A Gao, Joe
%A Li, Wenjie
%A Tan, Zhulin
%A Reeves, Jonathan T.
%A Wang, Jun
%A Lorenz, Jon C.
%A Li, Guisheng
%A Reeves, Diana C.
%A Premasiri, Ajith
%A Grinberg, Nelu
%A Haddad, Nizar
%A Lu, Bruce Z.
%A Song, Jinhua J.
%A Senanayake, Chris H.
%D 2013
%T Asymmetric Methallylation of Ketones Catalyzed by a Highly Active Organocatalyst 3,3′‑F2‑BINOL
%U https://acs.figshare.com/articles/journal_contribution/Asymmetric_Methallylation_of_Ketones_Catalyzed_by_a_Highly_Active_Organocatalyst_3_3_F_sub_2_sub_BINOL/2427478
%R 10.1021/ol400498a.s001
%2 https://acs.figshare.com/ndownloader/files/4069696
%K Asymmetric Methallylation
%K enantioselectivity
%K loading
%K Ketones Catalyzed
%K methallylation
%K Organocatalyst
%K mol
%K ketone
%K organocatalyst
%K catalyst
%X (S)-3,3′-F2-BINOL has been synthesized for the first time and demonstrated as a highly active organocatalyst for asymmetric methallylation of ketones. Up to 98:2 enantioselectivity and 99% yield were obtained with 5 mol % catalyst loading. The catalyst (S)-3,3′-F2-BINOL could be easily recovered and reused.
%I ACS Publications