%0 Journal Article %A Zhang, Yongda %A Li, Ning %A Qu, Bo %A Ma, Shengli %A Lee, Heewon %A Gonnella, Nina C. %A Gao, Joe %A Li, Wenjie %A Tan, Zhulin %A Reeves, Jonathan T. %A Wang, Jun %A Lorenz, Jon C. %A Li, Guisheng %A Reeves, Diana C. %A Premasiri, Ajith %A Grinberg, Nelu %A Haddad, Nizar %A Lu, Bruce Z. %A Song, Jinhua J. %A Senanayake, Chris H. %D 2013 %T Asymmetric Methallylation of Ketones Catalyzed by a Highly Active Organocatalyst 3,3′‑F2‑BINOL %U https://acs.figshare.com/articles/journal_contribution/Asymmetric_Methallylation_of_Ketones_Catalyzed_by_a_Highly_Active_Organocatalyst_3_3_F_sub_2_sub_BINOL/2427478 %R 10.1021/ol400498a.s001 %2 https://acs.figshare.com/ndownloader/files/4069696 %K Asymmetric Methallylation %K enantioselectivity %K loading %K Ketones Catalyzed %K methallylation %K Organocatalyst %K mol %K ketone %K organocatalyst %K catalyst %X (S)-3,3′-F2-BINOL has been synthesized for the first time and demonstrated as a highly active organocatalyst for asymmetric methallylation of ketones. Up to 98:2 enantioselectivity and 99% yield were obtained with 5 mol % catalyst loading. The catalyst (S)-3,3′-F2-BINOL could be easily recovered and reused. %I ACS Publications