%0 Journal Article
%A Zonouzi, Afsaneh
%A Hosseinzadeh, Fatemeh
%A Karimi, Nastaran
%A Mirzazadeh, Roghieh
%A Ng, Seik Weng
%D 2016
%T Novel Approaches for the Synthesis of a Library of
Fluorescent Chromenopyrimidine Derivatives
%U https://acs.figshare.com/articles/journal_contribution/Novel_Approaches_for_the_Synthesis_of_a_Library_of_Fluorescent_Chromenopyrimidine_Derivatives/2415847
%R 10.1021/co300141j.s001
%2 https://acs.figshare.com/ndownloader/files/4056994
%K compound
%K domino reaction
%K Fluorescent Chromenopyrimidine DerivativesA library
%K Novel Approaches
%K 290 nm
%K chromenopyrimidine derivatives
%K fluorescence emission intensity
%K intramolecular H
%X A library of some new fluorescent
chromenopyrimidine derivatives
has been synthesized by new approaches. Water-promoted and one-pot
reaction can produce new dialkylylamino)-5H-chromeno[2,3-d]pyrimidin-2-yl) phenols. These compounds can also be produced
using domino reaction. Two parallel methods are compared. Novel N-alkyl-N-phenyl-5H-chromeno[2,3-d]-pyrimidin-4-amines and 4-alkoxy-5H-chromeno[2,
3-d]pyrimidines are synthesized by Lewis-acid
catalyzed reactions. The fluorescence emission intensity of the four
compounds from each of libraries after excitation in 290 nm is measured.
Compound 2-(4,5-bis(N-methyl-N-phenylamino)-5H-chromeno[2,3-d]pyrimidin-2-yl)phenol was isolated as a byproduct. The
details of an interesting exchangeable intramolecular H- bonding of
two of the new compounds are reported by X-ray analysis data.
%I ACS Publications