Solvent-Free Methallylboration of Ketones Accelerated
by <i>tert</i>-Alcohols
Yongda Zhang
Ning Li
Navneet Goyal
Guisheng Li
Heewon Lee
Bruce Z. Lu
Chris H. Senanayake
10.1021/jo4006574.s001
https://acs.figshare.com/articles/journal_contribution/Solvent_Free_Methallylboration_of_Ketones_Accelerated_by_i_tert_i_Alcohols/2407846
A solvent-
and metal-free process has been developed for the direct
methallylboration of ketones employing the stable <i>B</i>-methallylborinane <b>1</b>, which was accelerated by tertiary
alcohols. In the presence of 2.0 equiv of readily available tertiary
alcohols such as <i>tert</i>-amyl alcohol, the methallylation
products were prepared at room temperature in excellent yields. The
salient features of the described process include simple operation,
high efficiency, and mild reaction conditions.
2016-02-19 06:53:33
reaction conditions
methallylation products
2.0 equiv
room temperature