%0 Journal Article %A Liu, Xiang-Wei %A Shi, Jiang-Ling %A Yan, Jia-Xuan %A Wei, Jiang-Bo %A Peng, Kun %A Dai, Le %A Li, Chen-Guang %A Wang, Bi-Qin %A Shi, Zhang-Jie %D 2013 %T Reigoselective Arylation of Thiazole Derivatives at 5‑Position via Pd Catalysis under Ligand-Free Conditions %U https://acs.figshare.com/articles/journal_contribution/Reigoselective_Arylation_of_Thiazole_Derivatives_at_5_Position_via_Pd_Catalysis_under_Ligand_Free_Conditions/2352898 %R 10.1021/ol4027073.s001 %2 https://acs.figshare.com/ndownloader/files/3991402 %K Thiazole Derivatives %K ligand sets %K regioselective arylation %K ConditionsAn %K absence %K transformation %K Reigoselective Arylation %K activation %K Pd Catalysis %K method %K thiazole derivatives %X An efficient regioselective arylation of thiazole derivatives via Pd-catalyzed C–H activation is reported. The transformation was hypothesized through a Pd(0/II) catalytic cycle in the absence of special ligand sets. This method provided an efficient process to direct arylation of thiazoles at the 5-position. %I ACS Publications