%0 Generic %A Hashimoto, Takuya %A Gálvez, Alberto Osuna %A Maruoka, Keiji %D 2013 %T In Situ Assembled Boronate Ester Assisted Chiral Carboxylic Acid Catalyzed Asymmetric Trans-Aziridinations %U https://acs.figshare.com/articles/dataset/In_Situ_Assembled_Boronate_Ester_Assisted_Chiral_Carboxylic_Acid_Catalyzed_Asymmetric_Trans_Aziridinations/2348971 %R 10.1021/ja407764u.s002 %2 https://acs.figshare.com/ndownloader/files/3987421 %K Situ Assembled Boronate Ester Assisted Chiral Carboxylic %K chiral carboxylic acid catalyst %K boronate ester %K imine %K chiral Br ønsted acid catalyst %X We developed herein a new chiral Brønsted acid catalyst which is composed of two independent organic molecules, a chiral diol, and 2-boronobenzoic acid. In situ formation of a boronate ester was utilized as a key process to generate an active catalyst. This boronate ester assisted chiral carboxylic acid catalyst was successfully applied to the trans-aziridination of N-Boc and N-benzyl imines with N-phenyldiazoacetamide. This is the first catalyst to achieve high enantioselectivities using N-benzyl imines. %I ACS Publications