Fabrication
of Highly Uniform Gel Coatings by the
Conversion of Surface-Anchored Metal–Organic Frameworks
Manuel Tsotsalas
Jinxuan Liu
Beatrix Tettmann
Sylvain Grosjean
Artak Shahnas
Zhengbang Wang
Carlos Azucena
Matthew Addicoat
Thomas Heine
Joerg Lahann
Jörg Overhage
Stefan Bräse
Hartmut Gliemann
Christof Wöll
10.1021/ja409205s.s001
https://acs.figshare.com/articles/journal_contribution/Fabrication_of_Highly_Uniform_Gel_Coatings_by_the_Conversion_of_Surface_Anchored_Metal_Organic_Frameworks/2334337
We report the fabrication of 3D,
highly porous, covalently bound
polymer films of homogeneous thickness. These surface-bound gels combine
the advantages of metal–organic framework (MOF) materials,
namely, the enormous flexibility and the large size of the maximum
pore structures and, in particular, the possibility to grow them epitaxially
on modified substrates, with those of covalently connected gel materials,
namely, the absence of metal ions in the deposited material, a robust
framework consisting of covalent bonds, and, most importantly, pronounced
stability under biological conditions. The conversion of a SURMOF
(surface-mounted MOF) yields a surface-grafted gel. These SURGELs
can be loaded with bioactive compounds and applied as bioactive coatings
and provide a drug-release platform in in vitro cell culture studies.
2014-01-08 00:00:00
bioactive coatings
cell culture studies
covalent bonds
gel materials
bioactive compounds
metal ions
framework
SURGEL
polymer films
pore structures
SURMOF
Uniform Gel Coatings
3 D
MOF
covalently