General
Catalyst Control of the Monoisomerization
of 1‑Alkenes to <i>trans</i>-2-Alkenes
Casey
R. Larsen
Gulin Erdogan
Douglas B. Grotjahn
10.1021/ja411438d.s001
https://acs.figshare.com/articles/journal_contribution/General_Catalyst_Control_of_the_Monoisomerization_of_1_Alkenes_to_i_trans_i_2_Alkenes/2328286
After searching for the proper catalyst,
the dual challenges of
controlling the position of the double bond, and <i>cis</i>/<i>trans</i>-selectivity in isomerization of terminal
alkenes to their 2-isomers are finally met in a general sense by mixtures
of (C<sub>5</sub>Me<sub>5</sub>)Ru complexes <b>1</b> and <b>3</b> featuring a bifunctional phosphine. Typically, catalyst
loadings of 1 mol % of <b>1</b> and <b>3</b> can be employed
for the production of (<i>E</i>)-2-alkenes at 40–70
°C. Catalyst comprising <b>1</b> and <b>3</b> avoids
more than any other known example the thermodynamic equilibration
of alkene isomers, as the <i>trans</i>-2-alkenes of both
nonfunctionalized and functionalized alkenes are generated.
2014-01-29 00:00:00
terminal alkenes
bifunctional phosphine
General Catalyst Control
functionalized alkenes
C 5Me complexes 1
tran
catalyst loadings
alkene isomers