Ermolenko, Ludmila Zhaoyu, Hu Lejeune, Clarisse Vergne, Carine Ratinaud, Céline Nguyen, Thanh Binh Al-Mourabit, Ali Concise synthesis of Didebromohamacanthin A and Demethylaplysinopsine: Addition of Ethylenediamine and Guanidine Derivatives to the Pyrrole-Amino Acid Diketopiperazines in Oxidative Conditions Oxidative nucleophilic addition of ethylenediamine and guanidine derivatives to pyrrole-amino acid diketopiperazines was shown to provide substituted 5,6-dihydro-2­(1<i>H</i>)-piperazinones, quinoxalinones, and 2-aminoimidazolones. On the basis of this methodology, a concise approach to natural products didebromohamacanthin A and demethylaplysinopsine has been demonstrated. demethylaplysinopsine;Didebromohamacanthin;guanidine derivatives;acid;Concise synthesis;Guanidine Derivatives;methodology;approach;Diketopiperazine;Ethylenediamine;products didebromohamacanthin;diketopiperazine;Oxidative ConditionsOxidative nucleophilic addition;aminoimidazolone;basis;ethylenediamine;Demethylaplysinopsine;quinoxalinone;dihydro 2014-02-07
    https://acs.figshare.com/articles/journal_contribution/Concise_synthesis_of_Didebromohamacanthin_A_and_Demethylaplysinopsine_Addition_of_Ethylenediamine_and_Guanidine_Derivatives_to_the_Pyrrole_Amino_Acid_Diketopiperazines_in_Oxidative_Conditions/2325298
10.1021/ol4036177.s001