10.1021/ol500875e.s001 Karla Mahender Reddy Karla Mahender Reddy Vanipenta Yamini Vanipenta Yamini Kiran K. Singarapu Kiran K. Singarapu Subhash Ghosh Subhash Ghosh Synthesis of Proposed Aglycone of Mandelalide A American Chemical Society 2014 Brown crotylation olefination Prins cyclization Brown allylation reactions convergent synthesis 2014-05-16 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Synthesis_of_Proposed_Aglycone_of_Mandelalide_A/2292025 A highly convergent synthesis of the proposed mandelalide A aglycone is reported. The cornerstones of the synthetic strategy include the following: <i>E</i>-selective intramolecular Heck cyclization, Masamune–Roush olefination, Stork–Zhao–Wittig olefination, modified Prins cyclization; Sharpless asymmetric dihydroxylation followed by Williamson-type etherification, Julia–Kocienski olefination, Brown crotylation, and Brown allylation reactions.