10.1021/ac501586d.s002
Andrew Kucher
Andrew
Kucher
Lauren M. Jackson
Lauren M.
Jackson
Jordan O. Lerach
Jordan O.
Lerach
A. N. Bloom
A. N.
Bloom
N. J. Popczun
N. J.
Popczun
Andreas Wucher
Andreas
Wucher
Nicholas Winograd
Nicholas
Winograd
Near Infrared (NIR) Strong Field Ionization and Imaging
of C<sub>60</sub> Sputtered Molecules: Overcoming Matrix Effects and
Improving Sensitivity
American Chemical Society
2014
rubrene
SFI SNMS
mouse brain sections
SIMS
molecule
C 60 Sputtered Molecules
Botryococcus braunii algal cell colonies
SensitivityStrong field ionization
Overcoming Matrix Effects
Strong Field Ionization
NIR
signal
2014-09-02 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Near_Infrared_NIR_Strong_Field_Ionization_and_Imaging_of_C_sub_60_sub_Sputtered_Molecules_Overcoming_Matrix_Effects_and_Improving_Sensitivity/2258923
Strong field ionization (SFI) was
applied for the secondary neutral
mass spectrometry (SNMS) of patterned rubrene films, mouse brain sections,
and Botryococcus braunii algal cell
colonies. Molecular ions of rubrene, cholesterol, C<sub>31</sub> diene/triene,
and three wax monoesters were detected, representing some of the largest
organic molecules ever ionized intact by a laser post-ionization experiment.
In rubrene, the SFI SNMS molecular ion signal was ∼4 times
higher than in the corresponding secondary-ion mass spectroscopy (SIMS)
analysis. In the biological samples, the achieved signal improvements
varied among molecules and sampling locations, with SFI SNMS, in some
cases, revealing analytes made completely undetectable by the influence
of matrix effects in SIMS.