Selective Formation of a <i>Z</i>‑Trisubstituted Double Bond Using a 1‑(<i>tert</i>-Butyl)tetrazolyl Sulfone LorenteAdriana AlbericioFernando ÁlvarezMercedes 2014 In our effort to gain further insight into the enantioselective synthesis of the structural core of phormidolides B and C, we have discovered the formation of a <i>Z</i>-trisubstituted double bond. Here, we describe a highly selective process that can be applied to our target following a strategy that is based on Julia–Kocienski olefination. The use of 1-(<i>tert</i>-butyl)­tetrazolyl sulfone affords the construction of the <i>Z</i>-trisubstituted alkene with high efficiency and stereoselectivity.