10.1021/ol5034139.s001 Dandan Han Dandan Han Zhiming Li Zhiming Li Renhua Fan Renhua Fan Oxidative Nucleophilic Cyclization of 2‑Alkynylanilines with Thiophenols under Metal-Free Conditions American Chemical Society 2014 PhI ConditionsAn alkynylaniline thiophenol dearomatization Br ønsted acid nucleophilic cyclization DFT calculations oxidative Oxidative Nucleophilic Cyclization Alkynylaniline Thiophenol reaction pathway 2014-12-19 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Oxidative_Nucleophilic_Cyclization_of_2_Alkynylanilines_with_Thiophenols_under_Metal_Free_Conditions/2224024 An oxidative nucleophilic cyclization of 2-alkynylanilines with thiophenols under metal-free conditions was developed. The one-pot two-step reaction involves a PhI­(OAc)<sub>2</sub>-mediated oxidative dearomatization and a Brønsted acid promoted nucleophilic cyclization. DFT calculations were performed to understand the reaction pathway.