One-Pot Process That Efficiently Generates Single Stereoisomers of 1,3-Bisphosphinylpropanes Having Five Chiral Centers ZhangHe SunYong-Ming ZhaoYalei ZhouZhong-Yang WangJi-Ping XinNana NieShao-Zhen ZhaoChang-Qiu HanLi-Biao 2015 <i>P,C</i>-Stereogenic 1,3-bisphosphinylpropanes <b>3</b> that have up to five stereogenic centers could be obtained stereoselectively in high yields by a one-step reaction of (<i>R</i><sub>P</sub>)-menthylphenylphosphine oxide <b>1</b> with α,β-unsaturated aldehydes <b>2</b> catalyzed by KOH at room temperature. A mechanism was proposed as to involve a stereoselective intermolecular 1,3′-phosphorus migration from the 1,2-adduct of <b>1</b> with <b>2</b> to another <b>2</b> generating a 1,4-adduct that subsequently reacts with <b>1</b> to produce <b>3</b>.