10.1021/ac504868w.s001
Muyi He
Muyi
He
Zhenhua Xue
Zhenhua
Xue
Yinna Zhang
Yinna
Zhang
Zejian Huang
Zejian
Huang
Xiang Fang
Xiang
Fang
Feng Qu
Feng
Qu
Zheng Ouyang
Zheng
Ouyang
Wei Xu
Wei
Xu
Development and Characterizations of a Miniature Capillary
Electrophoresis Mass Spectrometry System
American Chemical Society
2015
charge competition effects
nanoelectrospray ionization
pressure ionization sources
DAPI
Miniature Capillary Electrophoresis Mass Spectrometry SystemA
MS instrument
pressure interface
isobaric peptides
capillary electrophoresis mass spectrometry
CE device
MS system
2015-02-17 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Development_and_Characterizations_of_a_Miniature_Capillary_Electrophoresis_Mass_Spectrometry_System/2195401
A miniature capillary electrophoresis
mass spectrometry (CE/MS)
system has been developed in this work. A 100% electrical driven miniaturized
CE device was integrated with a miniature MS instrument, which has
a discontinuous atmospheric pressure interface (DAPI) for coupling
with atmospheric pressure ionization sources. A nanoelectrospray ionization
(nano-ESI) source was developed with a sheath liquid interface for
coupling the miniature CE and the MS system. A systematic characterization
and optimization of the analytical performance have been done. The
analysis of isobaric peptides and avoiding charge competition effects
in nano-ESI sources have been demonstrated.