C–H
Activation/Functionalization Catalyzed
by Simple, Well-Defined Low-Valent Cobalt Complexes
Brendan
J. Fallon
Etienne Derat
Muriel Amatore
Corinne Aubert
Fabrice Chemla
Franck Ferreira
Alejandro Perez-Luna
Marc Petit
10.1021/ja512728f.s009
https://acs.figshare.com/articles/dataset/C_H_Activation_Functionalization_Catalyzed_by_Simple_Well_Defined_Low_Valent_Cobalt_Complexes/2192833
A facile
C–H activation and functionalization of aromatic
imines is presented using low-valent cobalt catalysts. Using Co(PMe<sub>3</sub>)<sub>4</sub> as catalyst we have developed an efficient and
simple protocol for the C–H/hydroarylation of alkynes with
an <i>anti</i> selectivity. Deuterium-labeling experiments,
DFT calculations coupled with the use of a well-defined catalyst have
for the first time shed light on the elusive black box of cobalt catalyzed
C–H functionalization.
2015-02-25 00:00:00
cobalt
functionalization
DFT calculations
catalyst