Yang, Xiao-Fei Hu, Xu-Hong Loh, Teck-Peng Expedient Synthesis of Pyrroloquinolinones by Rh-Catalyzed Annulation of <i>N</i>‑Carbamoyl Indolines with Alkynes through a Directed C–H Functionalization/C–N Cleavage Sequence A Rh-catalyzed redox-neutral C–H functionalization of <i>N</i>-carbamoyl indolines with various internal alkynes has been developed. The reaction, which involves the sequential cleavage of the C–H bond of the indoline at the C7-position and the C–N bond of the urea motif, provides a divergent protocol to rapidly assemble fused-ring pyrrolo­quinolinone analogues by using a direct alkenylation/annulation strategy with high efficiency and selectivity. Indoline;Annulation;selectivity;Expedient Synthesis;Functionalization;analogue;indoline;sequential cleavage;Pyrroloquinolinone;strategy;functionalization;SequenceA;Alkyne;efficiency;pyrrolo;Cleavage;alkyne;urea motif;alkenylation;bond 2015-03-20
    https://acs.figshare.com/articles/dataset/Expedient_Synthesis_of_Pyrroloquinolinones_by_Rh_Catalyzed_Annulation_of_i_N_i_Carbamoyl_Indolines_with_Alkynes_through_a_Directed_C_H_Functionalization_C_N_Cleavage_Sequence/2184442
10.1021/acs.orglett.5b00355.s004