%0 Generic %A Debnath, Sudarshan %A Mondal, Shovan %D 2015 %T One-Pot Sonogashira Coupling–Cyclization toward Regioselective Synthesis of Benzosultams %U https://acs.figshare.com/articles/dataset/One_Pot_Sonogashira_Coupling_Cyclization_toward_Regioselective_Synthesis_of_Benzosultams/2175577 %R 10.1021/acs.joc.5b00274.s002 %2 https://acs.figshare.com/ndownloader/files/3809503 %K Regioselective Synthesis %K terminal alkynes %K yield %K access %K variety %K cyclization %K BenzosultamsA %K method %K regioselectivity %K DFT %K benzosultams regioselectively %K density %K bromobenzenesulfonamide %K Sonogashira %X A one-pot method for the Sonogashira coupling and cyclization of 2-bromobenzenesulfonamides and terminal alkynes is presented. This method allows access to a variety of substituted benzosultams regioselectively in excellent yields. The reasons for regioselectivity are interpreted through density functional theory (DFT) studies. %I ACS Publications