10.1021/jacs.5b01707.s002 Jun Zheng Jun Zheng Shao-Bo Wang Shao-Bo Wang Chao Zheng Chao Zheng Shu-Li You Shu-Li You Asymmetric Dearomatization of Naphthols via a Rh-Catalyzed C(sp<sup>2</sup>)–H Functionalization/Annulation Reaction American Chemical Society 2015 enantioenriched spirocyclic enones presence Functionalization stereogenic enantioselective quaternary functionalization Naphthol yield ReactionA catalyst oxidant center chiral Asymmetric Dearomatization dearomatization alkyne aryl Cp Cu 2015-04-22 00:00:00 Dataset https://acs.figshare.com/articles/dataset/Asymmetric_Dearomatization_of_Naphthols_via_a_Rh_Catalyzed_C_sp_sup_2_sup_H_Functionalization_Annulation_Reaction/2174257 A Rh-catalyzed enantioselective dearomatization of 1-aryl-2-naphthols with internal alkynes via C–H functionalization reaction was achieved. In the presence of a chiral Cp/Rh catalyst and combined oxidants of Cu­(OAc)<sub>2</sub> and air (oxygen), various highly enantioenriched spirocyclic enones bearing an all-carbon quaternary stereogenic center could be synthesized in 33–98% yields with up to 97:3 er.