%0 Journal Article
%A Li, Xin
%A Wang, Man-Man
%A Zheng, Guo-Ying
%A Ai, Lian-Feng
%A Wang, Xue-Sheng
%D 2015
%T Fast and Online Determination of Five Avermectin Residues in Foodstuffs
of Plant and Animal Origin Using Reusable Polymeric Monolithic Extractor
Coupled with LC-MS/MS
%U https://acs.figshare.com/articles/journal_contribution/Fast_and_Online_Determination_of_Five_Avermectin_Residues_in_Foodstuffs_of_Plant_and_Animal_Origin_Using_Reusable_Polymeric_Monolithic_Extractor_Coupled_with_LC_MS_MS/2172238
%R 10.1021/acs.jafc.5b00739.s003
%2 https://acs.figshare.com/ndownloader/files/3806161
%K Animal Origin
%K 500 experiments
%K detection limit
%K SPE
%K 15 min
%K Avermectin Residues
%K Online Determination
%K 4OH
%K monolith
%K MeCN
%K chili seed
%K NH
%K C 18
%K avermectin residues
%K determination
%K mm
%K animal origin
%K Reusable Polymeric Monolithic Extractor
%X A hydrophobic monolith (10 mm ×
2.1 mm i.d.) was developed as a reusable online solid-phase extraction
(SPE) sorbent coupled with LC-MS/MS for the rapid determination of
five avermectin residues in foodstuffs of both plant and animal origin.
The online SPE was achieved using a 10 mmol/L ammonium acetate solution
as the loading solvent, and acetonitrile (MeCN) was selected for the
washing step. After being transferred from the monolith into a C18 analytical column using MeCN, the analytes were analyzed
by LC-MS/MS using MeCN/0.1% NH4OH (10:90, v/v) as the mobile
phase. The detection limit was 2 μg/kg for five avermectins,
and the recoveries in fresh pear, chili seed, bovine muscle, and milk
ranged from 71.8% to 101.3% with relative standard deviations of less
than 8.94%. The online SPE and determination were achieved within
15 min, and the monolithic extractor was reusable for more than 500
experiments.
%I ACS Publications