%0 Journal Article %A Li, Xin %A Wang, Man-Man %A Zheng, Guo-Ying %A Ai, Lian-Feng %A Wang, Xue-Sheng %D 2015 %T Fast and Online Determination of Five Avermectin Residues in Foodstuffs of Plant and Animal Origin Using Reusable Polymeric Monolithic Extractor Coupled with LC-MS/MS %U https://acs.figshare.com/articles/journal_contribution/Fast_and_Online_Determination_of_Five_Avermectin_Residues_in_Foodstuffs_of_Plant_and_Animal_Origin_Using_Reusable_Polymeric_Monolithic_Extractor_Coupled_with_LC_MS_MS/2172238 %R 10.1021/acs.jafc.5b00739.s003 %2 https://acs.figshare.com/ndownloader/files/3806161 %K Animal Origin %K 500 experiments %K detection limit %K SPE %K 15 min %K Avermectin Residues %K Online Determination %K 4OH %K monolith %K MeCN %K chili seed %K NH %K C 18 %K avermectin residues %K determination %K mm %K animal origin %K Reusable Polymeric Monolithic Extractor %X A hydrophobic monolith (10 mm × 2.1 mm i.d.) was developed as a reusable online solid-phase extraction (SPE) sorbent coupled with LC-MS/MS for the rapid determination of five avermectin residues in foodstuffs of both plant and animal origin. The online SPE was achieved using a 10 mmol/L ammonium acetate solution as the loading solvent, and acetonitrile (MeCN) was selected for the washing step. After being transferred from the monolith into a C18 analytical column using MeCN, the analytes were analyzed by LC-MS/MS using MeCN/0.1% NH4OH (10:90, v/v) as the mobile phase. The detection limit was 2 μg/kg for five avermectins, and the recoveries in fresh pear, chili seed, bovine muscle, and milk ranged from 71.8% to 101.3% with relative standard deviations of less than 8.94%. The online SPE and determination were achieved within 15 min, and the monolithic extractor was reusable for more than 500 experiments. %I ACS Publications