10.1021/acs.joc.5b00331.s002
Dattatraya H. Dethe
Dattatraya H.
Dethe
Balu D. Dherange
Balu D.
Dherange
Enantioselective Total
Syntheses of (+)-Hostmanin
A, (−)-Linderol A, (+)-Methyllinderatin and Structural Reassignment
of Adunctin E
American Chemical Society
2015
Enantioselective
linderol
series
Synthese
enantioselective synthesis
method
product adunctin E
Hostmanin
Methyllinderatin
hexahydrodibenzofuran derivatives
spectroscopic data investigations
Adunctin EA
Friedel
hostmanin
methyllinderatin
Linderol
analysis
reassignment
Structural Reassignment
2015-05-01 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Enantioselective_Total_Syntheses_of_Hostmanin_A_Linderol_A_Methyllinderatin_and_Structural_Reassignment_of_Adunctin_E/2170648
A one-step protocol has been developed
for the enantioselective
synthesis of hexahydrodibenzofuran derivatives using a modified Friedel–Crafts
reaction. The developed method was applied to the synthesis of a series
of natural products including (+)-hostmanin A, (+)-methyllinderatin,
and (−)-linderol A. The synthetic and spectroscopic data investigations
led to the structural reassignment of natural product adunctin E,
which was further confirmed by single-crystal X-ray analysis.