10.1021/acs.inorgchem.5b00450.s001 Indranil Sinha Indranil Sinha Alexander Hepp Alexander Hepp Birgitta Schirmer Birgitta Schirmer Jutta Kösters Jutta Kösters Johannes Neugebauer Johannes Neugebauer Jens Müller Jens Müller Regioselectivity of the C‑Metalation of 6‑Furylpurine: Importance of Directing Effects American Chemical Society 2015 Regioselectivity Pt furyl carbon atoms Pd α position regioselectivity ligand Importance N 7 purine atom furyl moiety Hg β position metal ions Furylpurine bidentate fashion Directing EffectsWe report furylpurine metal ion 2015-05-04 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Regioselectivity_of_the_C_Metalation_of_6_Furylpurine_Importance_of_Directing_Effects/2170189 We report the C-metalation of 6-furylpurine with Pt<sup>2+</sup>, Pd<sup>2+</sup>, and Hg<sup>2+</sup>. The ligand binds the metal ions in a bidentate fashion, involving the N7 purine atom and one of the furyl carbon atoms. The regioselectivity is determined by the metal ion. Pt<sup>2+</sup> and Pd<sup>2+</sup> coordinate the furyl moiety in its β position and Hg<sup>2+</sup> in its electronically preferred α position.