10.1021/acs.inorgchem.5b00450.s001
Indranil Sinha
Indranil
Sinha
Alexander Hepp
Alexander
Hepp
Birgitta Schirmer
Birgitta
Schirmer
Jutta Kösters
Jutta
Kösters
Johannes Neugebauer
Johannes
Neugebauer
Jens Müller
Jens
Müller
Regioselectivity of the C‑Metalation of 6‑Furylpurine:
Importance of Directing Effects
American Chemical Society
2015
Regioselectivity
Pt
furyl carbon atoms
Pd
α position
regioselectivity
ligand
Importance
N 7 purine atom
furyl moiety
Hg
β position
metal ions
Furylpurine
bidentate fashion
Directing EffectsWe report
furylpurine
metal ion
2015-05-04 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Regioselectivity_of_the_C_Metalation_of_6_Furylpurine_Importance_of_Directing_Effects/2170189
We report the C-metalation of 6-furylpurine
with Pt<sup>2+</sup>, Pd<sup>2+</sup>, and Hg<sup>2+</sup>. The ligand
binds the metal ions in a bidentate fashion, involving the N7 purine
atom and one of the furyl carbon atoms. The regioselectivity is determined
by the metal ion. Pt<sup>2+</sup> and Pd<sup>2+</sup> coordinate the
furyl moiety in its β position and Hg<sup>2+</sup> in its electronically
preferred α position.