%0 Journal Article
%A Morales-Narváez, Eden
%A Naghdi, Tina
%A Zor, Erhan
%A Merkoçi, Arben
%D 2015
%T Photoluminescent Lateral-Flow Immunoassay Revealed
by Graphene Oxide: Highly Sensitive Paper-Based Pathogen Detection
%U https://acs.figshare.com/articles/journal_contribution/Photoluminescent_Lateral_Flow_Immunoassay_Revealed_by_Graphene_Oxide_Highly_Sensitive_Paper_Based_Pathogen_Detection/2140195
%R 10.1021/acs.analchem.5b02383.s001
%2 https://acs.figshare.com/ndownloader/files/3774049
%K Immunoassay
%K Escherichia coli
%K Photoluminescent
%K Pathogen
%K graphene oxide
%K performance
%K Revealed
%K mL
%K Sensitive
%K flow immunoassay
%K device
%K pathogen detection
%K DetectionA
%K model pathogen
%K photoluminescence quenching ability
%K Graphene Oxide
%K diagnostics applications
%K CFU
%K antibody
%K display
%X A paper-based lateral flow immunoassay
for pathogen detection that
avoids the use of secondary antibodies and is revealed by the photoluminescence
quenching ability of graphene oxide is reported. Escherichia
coli has been selected as a model pathogen. The proposed
device is able to display a highly specific and sensitive performance
with a limit of detection of 10 CFU mL–1 in standard
buffer and 100 CFU mL–1 in bottled water and milk.
This low-cost disposable and easy-to-use device will prove valuable
for portable and automated diagnostics applications.
%I ACS Publications