10.1021/acs.analchem.5b02383.s001
Eden Morales-Narváez
Eden
Morales-Narváez
Tina Naghdi
Tina
Naghdi
Erhan Zor
Erhan
Zor
Arben Merkoçi
Arben
Merkoçi
Photoluminescent Lateral-Flow Immunoassay Revealed
by Graphene Oxide: Highly Sensitive Paper-Based Pathogen Detection
American Chemical Society
2015
Immunoassay
Escherichia coli
Photoluminescent
Pathogen
graphene oxide
performance
Revealed
mL
Sensitive
flow immunoassay
device
pathogen detection
DetectionA
model pathogen
photoluminescence quenching ability
Graphene Oxide
diagnostics applications
CFU
antibody
display
2015-08-18 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Photoluminescent_Lateral_Flow_Immunoassay_Revealed_by_Graphene_Oxide_Highly_Sensitive_Paper_Based_Pathogen_Detection/2140195
A paper-based lateral flow immunoassay
for pathogen detection that
avoids the use of secondary antibodies and is revealed by the photoluminescence
quenching ability of graphene oxide is reported. <i>Escherichia
coli</i> has been selected as a model pathogen. The proposed
device is able to display a highly specific and sensitive performance
with a limit of detection of 10 CFU mL<sup>–1</sup> in standard
buffer and 100 CFU mL<sup>–1</sup> in bottled water and milk.
This low-cost disposable and easy-to-use device will prove valuable
for portable and automated diagnostics applications.