10.1021/acs.orglett.5b02559.s001 Kirsten F. Johnson Kirsten F. Johnson Adam C. Schmidt Adam C. Schmidt Levi M. Stanley Levi M. Stanley Rhodium-Catalyzed, Enantioselective Hydroacylation of <i>ortho</i>-Allylbenzaldehydes American Chemical Society 2015 yield Rh hydroacylation reactions Enantioselective Hydroacylation alkene isomerization ee enantioselectivitie formation endo dihydro pathway enantioselective hydroacylation rhodium catalyst byproduct NaBARF 2015-10-02 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Rhodium_Catalyzed_Enantioselective_Hydroacylation_of_i_ortho_i_Allylbenzaldehydes/2126569 The development of a rhodium catalyst for <i>endo</i>- and enantioselective hydroacylation of <i>ortho</i>-allylbenz­aldehydes is reported. A catalyst generated <i>in situ</i> from [Rh­(COD)­Cl]<sub>2</sub>, (<i>R</i>)-DTBM-SEGPHOS, and NaBARF promotes the desired hydroacylation reactions and minimizes the formation of byproducts from competitive alkene isomerization and ene/dehydration pathways. These rhodium-catalyzed processes generate the 3,4-dihydro­naphthalen-1­(2<i>H</i>)-one products in moderate-to-high yields (49–91%) with excellent enantioselectivities (96–99% ee).