Dearomative Indole Bisfunctionalization via a Diastereoselective Palladium-Catalyzed Arylcyanation David A. Petrone Andy Yen Nicolas Zeidan Mark Lautens 10.1021/acs.orglett.5b02403.s004 https://acs.figshare.com/articles/dataset/Dearomative_Indole_Bisfunctionalization_via_a_Diastereoselective_Palladium_Catalyzed_Arylcyanation/2126452 The first Pd-catalyzed dearomative indole bisfunctionalization via a diastereoselective arylcyanation is reported. This method facilitates the formation of diverse indoline scaffolds bearing congested stereocenters with high levels of diastereoselectivity. This also represents the first example of a cyanation mechanism involving a 2° benzylic Pd­(II) intermediate. 2015-10-02 00:00:00 cyanation mechanism diastereoselectivity Pd bisfunctionalization diastereoselective arylcyanation indole Dearomative Indole Bisfunctionalization ArylcyanationThe method stereocenter dearomative formation benzylic Diastereoselective indoline scaffolds