10.1021/acs.nanolett.5b02859.s002 Yihua Loo Yihua Loo Anupama Lakshmanan Anupama Lakshmanan Ming Ni Ming Ni Lai Ling Toh Lai Ling Toh Shi Wang Shi Wang Charlotte A. E. Hauser Charlotte A. E. Hauser Peptide Bioink: Self-Assembling Nanofibrous Scaffolds for Three-Dimensional Organotypic Cultures American Chemical Society 2015 40 kPa biocompatible scaffolds support tissue engineering Peptide Bioink stiffness 2015-10-14 00:00:00 Media https://acs.figshare.com/articles/media/Peptide_Bioink_Self_Assembling_Nanofibrous_Scaffolds_for_Three_Dimensional_Organotypic_Cultures/2122429 Printable scaffolds with adequate mechanical strength and stiffness are sought after to ensure viability of printed cells and tissues. We report the first peptide bioinks–lysine-containing hexapeptides that self-assemble into stable, nanofibrous three-dimensional hydrogels with unprecedented stiffness of up to 40 kPa. These biocompatible scaffolds support the three-dimensional culture of human stem cells and differentiation of primary cells into organotypic (gastrointestinal and skin) structures for high-throughput screening, diagnosis, and tissue engineering.