The Mosaic of Rottlerin
Kenneth
K. C. Hong
Graham E. Ball
David StC. Black
Naresh Kumar
10.1021/acs.joc.5b01827.s003
https://acs.figshare.com/articles/dataset/The_Mosaic_of_Rottlerin/2111869
The first total synthesis of rottlerin
is described. The methodology
allows the development of potential novel protein kinase C δ
(PKCδ) analogues for better treatment of various diseases. Kamalachalcone
A and dimeric rottlerin were synthesized in a very practical and economical
way using FeCl<sub>3</sub> as a catalyst.
2015-11-06 00:00:00
novel protein kinase C δ
dimeric rottlerin
analogue
PKC
methodology
Mosaic
Kamalachalcone
catalyst
FeCl 3
RottlerinThe
synthesis