10.1021/acs.orglett.5b01307.s001
Shing-Hing Lau
Shing-Hing
Lau
Alicia Galván
Alicia
Galván
Rohan
R. Merchant
Rohan
R.
Merchant
Claudio Battilocchio
Claudio
Battilocchio
José A. Souto
José A.
Souto
Malcolm
B. Berry
Malcolm
B.
Berry
Steven V. Ley
Steven V.
Ley
Machines vs Malaria: A Flow-Based Preparation of the
Drug Candidate OZ439
American Chemical Society
2015
batch processes
machines vs Malaria
approach
Drug Candidate OZ 439An
Preparation
antimalarial
intermediate
candidate
target molecule
preparation
2015-12-22 22:41:20
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Machines_vs_Malaria_A_Flow_Based_Preparation_of_the_Drug_Candidate_OZ439/2057466
An
efficient preparation of the antimalarial drug candidate OZ439,
which was obtained by integrating a machine-assisted approach with
batch processes, is reported. This approach allows a rapid and cost-effective
production of the key intermediates that were readily elaborated into
the target molecule.