Khatib, Mirna El Molander, Gary A. Copper(II)-Mediated <i>O</i>‑Arylation of Protected Serines and Threonines An effective protocol toward the <i>O</i>-arylation of β-hydroxy-α-amino acid substrates serine and threonine has been developed via Chan–Lam cross-coupling. This Cu­(II)-catalyzed transformation involves benign open-flask conditions that are well-tolerated with a variety of protected (Boc-, Cbz-, Tr-, and Fmoc-) serine and threonine derivatives and various potassium organotrifluoroborates and boronic acids. Protected Serines;threonine derivatives;Boc;potassium organotrifluoroborates;variety;transformation;serine;Tr;Fmoc;boronic acids;substrate;ThreoninesAn;Chan;Cbz;hydroxy;Cu 2015-12-17
    https://acs.figshare.com/articles/journal_contribution/Copper_II_Mediated_i_O_i_Arylation_of_Protected_Serines_and_Threonines/2040516
10.1021/ol5024689.s001