10.1021/acs.jced.9b00743.s001 Mengyao An Mengyao An Jingxuan Qiu Jingxuan Qiu Dengjing Yi Dengjing Yi Haoyou Liu Haoyou Liu Shen Hu Shen Hu Jiaming Han Jiaming Han Haishuang Huang Haishuang Huang Hui He Hui He Conglei Liu Conglei Liu Ziyi Zhao Ziyi Zhao Yan Shi Yan Shi Peng Wang Peng Wang Measurement and Correlation for Solubility of l‑Alanine in Pure and Binary Solvents at Temperatures from 283.15 to 323.15 K American Chemical Society 2020 323.15 K 1- butanol 2- methyl -1-propanol 1- pentanol ethyl acetate 1- propanol solvent 2- propanol solubility ethanol acetone methanol 2020-01-09 20:50:31 Journal contribution https://acs.figshare.com/articles/journal_contribution/Measurement_and_Correlation_for_Solubility_of_l_Alanine_in_Pure_and_Binary_Solvents_at_Temperatures_from_283_15_to_323_15_K/11561895 The solubility of l-alanine in five binary systems water + methanol, water + ethanol, water + 1-propanol, water + 2-propanol, and water + acetone and 12 neat solvents (water, 1-butanol, methanol, 2-butanol, 2-methyl-1-propanol, 1-pentanol, 1-propanol, ethanol, 2-propanol, ethyl acetate, acetonitrile, and acetone) was determined by the gravimetrical method within the temperature range from 283.15 to 323.15 K under atmospheric pressure. The experimental results indicated that the solubility increased with increasing temperature and mole ratio of water in all investigated solvents and decreased with the rise of the mole fraction of five different organic solvents in the binary solvent systems. The order of l-alanine solubility in the selected pure solvents was water > 1-butanol > methanol ≈ 2-butanol > 2-methyl-1-propanol ≈ 1-pentanol ≈ 1-propanol ≈ ethanol > 2-propanol > ethyl acetate > acetonitrile > acetone. The solubility was mathematically represented by the modified Apelblat, Jouyban–Acree, and Apelblat–Jouyban–Acree models. All the models can be found to agree well with the data in the experiment.