%0 Journal Article %A Gu, Xiao Ying %A Liu, Jia Jun %A Gao, Peng Fei %A Li, Yuan Fang %A Huang, Cheng Zhi %D 2019 %T Gold Triangular Nanoplates Based Single-Particle Dark-Field Microscopy Assay of Pyrophosphate %U https://acs.figshare.com/articles/journal_contribution/Gold_Triangular_Nanoplates_Based_Single-Particle_Dark-Field_Microscopy_Assay_of_Pyrophosphate/11310491 %R 10.1021/acs.analchem.9b04093.s001 %2 https://acs.figshare.com/ndownloader/files/20046581 %K surface plasmon resonance %K LSPR %K PPi %K intensity %K Single-Particle Dark-Field Microscopy Assay %K copper ions %K gold Triangular Nanoplates %K AuNPL %K DFM %K etching %X Owing to the sharp edge-enhanced electric field, gold triangular nanoplates (AuNPLs) exhibit strong localized surface plasmon resonance (LSPR) scattering and display as red spots with high intensity and narrow distribution under dark-field microscopy (DFM), based on which sensitive sensing applications could be developed. As a concept of proof, the inhibition effects of pyrophosphate (PPi) against the etching of AuNPLs based on Cu2+ and I mediated is dynamically monitored. The etching proceeding of AuNPLs by copper ions and iodide ions leads to the gradually blue-shifted LSPR scattering color of AuNPLs under DFM from the original red to green, accompanied by the reduced LSPR scattering intensity. As a result of the strong affinity of PPi to copper ions, the presence of PPi makes the etching process greatly suppressed, thereby achieving sensitive detection of the PPi. %I ACS Publications