Leonard, David K. Li, Wu Junge, Kathrin Beller, Matthias Improved Bimetallic Cobalt–Manganese Catalysts for Selective Oxidative Cleavage of Morpholine Derivatives Catalytic methods for the site-selective scission of C­(sp<sup>3</sup>)–C­(sp<sup>3</sup>) bonds remain scarcely explored in contrast to the vast literature on C–C coupling. In view of this, we report a means of oxidative C–C single-bond cleavage in morpholines, made possible by a synergy between cobalt and manganese catalysts using air as a benign oxidant. We demonstrate the synthetic utility of this system with the late-stage oxidative cleavage of Linezolid. Linezolid;cobalt;synergy;utility;site-selective scission;Bimetallic;Catalyst;contrast;single-bond;oxidant;late-stage oxidative cleavage;Selective Oxidative Cleavage;manganese catalysts;Morpholine Derivatives Catalytic methods;Cobalt;morpholine;bond 2019-11-08
    https://acs.figshare.com/articles/journal_contribution/Improved_Bimetallic_Cobalt_Manganese_Catalysts_for_Selective_Oxidative_Cleavage_of_Morpholine_Derivatives/10274807
10.1021/acscatal.9b03476.s001