%0 Journal Article
%A Wang, Xiaofeng
%A Ou, Yingcong
%A Peng, Zhenbo
%A Yu, Guodian
%A Huang, Yuanting
%A Li, Xianwei
%A Huo, Yanping
%A Chen, Qian
%D 2019
%T TBHP/NH4I‑Mediated
Direct N–H
Phosphorylation of Imines and Imidates
%U https://acs.figshare.com/articles/journal_contribution/TBHP_NH_sub_4_sub_I_Mediated_Direct_N_H_Phosphorylation_of_Imines_and_Imidates/10048487
%R 10.1021/acs.joc.9b02301.s001
%2 https://acs.figshare.com/ndownloader/files/18108935
%K TBHP
%K Imidate
%K I-mediated
%K group compatibility
%K phosphoryl
%K imine
%K Imine
%K transformation
%K Phosphorylation
%K metal-free
%K construction
%K formation
%K cross-dehydrogenative
%K compound
%K CDC
%K phosphorylation
%K bond
%X A direct
and practical metal-free N–H phosphorylation has
been achieved via the TBHP/NH4I-mediated cross-dehydrogenative
coupling (CDC) reactions between imines/imidates and P(O)H compounds.
This transformation provides an efficient synthetic route to the construction
of P–N bonds with good functional group compatibility, leading
to the formation of N-phosphorylimines and N-phosphorylimidates in up to 95% yield (33 examples)
under mild conditions.
%I ACS Publications