10.1021/acsami.9b15349.s001
Jingjing Shen
Jingjing
Shen
Lei Zhang
Lei
Zhang
Li Liu
Li
Liu
Bin Wang
Bin
Wang
Jieqiong Bai
Jieqiong
Bai
Chao Shen
Chao
Shen
Yu Chen
Yu
Chen
Quli Fan
Quli
Fan
Shufen Chen
Shufen
Chen
Weibing Wu
Weibing
Wu
Xiaomiao Feng
Xiaomiao
Feng
Lianhui Wang
Lianhui
Wang
Wei Huang
Wei
Huang
Revealing
Lectin–Sugar Interactions with a
Single Au@Ag Nanocube
American Chemical Society
2019
surface plasmon resonance
biosensor system
dark-field microscopy images
novel plasmonic nanobiosensors
detection
monitoring
nanobiosensor system
NC
trace concanavalin
biosensing ability
trace ConA
nanoparticle surface
LSPR spectra
nanoparticle-based plasmonic nanotechnology
lectin
2019-10-18 21:29:47
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Revealing_Lectin_Sugar_Interactions_with_a_Single_Au_Ag_Nanocube/10005470
An
individual nanoparticle-based plasmonic nanotechnology was used
for real-time monitoring of lectin–sugar interactions, which
could be designed as novel plasmonic nanobiosensors for the detection
of trace concanavalin A (ConA) with high sensitivity and selectivity.
The localized surface plasmon resonance (LSPR) spectra of Au@Ag nanocubes
(NCs) are linearly shifted to a long wavelength with an increasing
concentration of ConA. In fact, each Au@Ag NC can act as a nanobiosensor
for the quantified detection of trace ConA, which enables the miniaturization
of the biosensor system to nanoscale. Furthermore, the results demonstrated
the perfect biosensing ability with the dual channel of dark-field
microscopy images and LSPR spectra. We expect that this nanobiosensor
system can provide an alternative important method for monitoring
the specific binding of lectin–sugar at a single nanoparticle
surface.